New Development in Electron Microscopy Grid Vitrification

Linkam previewed its new cryo plunger—CryoGenium—an exciting new development in electron microscopy (EM) grid vitrification. Imaging of biological samples embedded in vitrified ice has become of great interest in recent years as it provides several advantages: the biological sample is in a fully hydrated state with superior preservation down to ultra structural level, a vitrified sample is naturally compatible with the vacuum required for EM/single particle (SPT)/correlative light and electron microscopy (CLEM), and cryo fluorescence provides very low photo-bleaching and high signal to noise imaging.

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