Key composition optimisation of meat processed protein source by vacuum freeze-drying technology using Linkam’s FDCS196

This study, using Linkam’s FDCS196 Freeze Drying System, shows how the freeze-drying process can be used to preserve meat and discusses the effect of system pressure on the freeze drying efficiency.

Access the application note here.

Prickett, Richelle C., et al. "Effect of supercooling and cell volume on intracellular ice formation." Cryobiology 70.2 (2015): 156-163.

Effect of supercooling and cell volume on intracellular ice formation using Linkam’s FDCS196

Studying the effect of supercooling and cell volume on intracellular ice formation (IIF), using Linkam’s Freeze Drying system the FDCS196.

Read the application note here.

Prickett, Richelle C., et al. "Effect of supercooling and cell volume on intracellular ice formation." Cryobiology 70.2 (2015): 156-163.

Using Linkam’s FDCS196 to Investigate How Small Molecule Ice Recrystallisation Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations

Researchers at the University of Ottowa, Canada used Linkam’s Freeze Drying system FDCS196 to cryopreserve red blood cells with slow cooling rates prior to storage at -80°C.

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Capicciotti, C.J. et al. Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations. Sci. Rep. 5, 9692; DOI:10.1038/srep09692 (2015).

Mannitol/l-Arginine-Based Formulation Systems for Freeze Drying of Protein Pharmaceuticals: Effect of the l-Arginine Counter Ion and Formulation Composition on the Formulation Properties.

In this study, Linkam’s FDCS196 was used to freeze dry pharmaceutical formulations to obtain partially crystalline solids. They show that these mannitol/l-arginine-based formulations can be freeze dried in a fast process to produce a viable cake structure.

Read the full paper here (access required).