The Linkam DSC600 stage allows direct coupling with optical methods, whether visual or spectroscopic. Particularly promising are combinations with UV/VIS, infrared, and Raman spectroscopy, as well as several X-ray techniques. In this way, additional information can be obtained simultaneously with thermoanalytical investigations, enabling a more comprehensive understanding of the processes involved.
Investigating the Simultaneous Optical and Thermoanalytical Monitoring of the Dehydration of Copper Sulphate Pentahydrate using Linkam's DSC600
Scientists investigated the simultaneous optical and thermoanalytical monitoring of the dehydration of copper sulphate pentahydrate using Linkam's DSC600 which allows direct coupling with optical methods, whether visual or spectroscopic. Simultaneous coupling with infrared and X-ray methods provides valuable information that goes far beyond the thermoanalytical results.
Deciphering the role of amphiphilic polymer combinations in the formation of ternary griseofulvin amorphous solid dispersions using Linkam's THMS600
Researchers at Aristotle University of Thessaloniki, NatPro-AUTH, CIRI-AUTH, in Greece used Linkam’s THMS600 to investigate how different combinations of amphiphilic polymers influence the formation, physical stability, and dissolution performance of ternary amorphous solid dispersions (ASDs) of griseofulvin (GRF), a poorly soluble drug with a strong tendency to recrystallise.
Investigating Fluid Inclusions in Sedimentary Rocks for Petroleum Geology and Carbon Sequestration Research using Linkam’s MDSG600 and LTS420E stages.
Linkam’s collaboration with Radiant streamlines electronic component testing using the HFS600E-PB4
Optimising Linkam’s Cryomicroscropy Portfolio: Developing the CMS196 V4 and CryoGenium.
Characterising the mechanical properties of synthetic spider silk using the Linkam Modular Force Stage (MFS)
Dr. Benjamin Schmuck and his team used a Linkam modular force stage (MFS) to further our understanding of spider silk’s mechanical properties – and potential applications.
Characterising the mechanical properties of synthetic spider silk using the Linkam Modular Force Stage (MFS)
Achieving precise temperature control in semiconductor and electronics research
Investigating the Effect of Temperature and Shear Flow on the Nucleation Rate of Spherulites in Isotactic Polypropylene using Linkam’s CSS450 Stage.
Characterising the Temperature-induced Evolution of the Shape and Texture of a Silicon Wafer.
Mechanical Characterisation: Understanding Materials Through Precise Tensile Testing
Tackling some of the world's most challenging biological issues with cryogenic microscopy using Linkam's state-of-the-art stages.
Studying a New Polymorph of Metacetamol using Linkam’s FTIR600
Replicating the texture of meat in plant-based alternatives using Linkam’s Modular Force Stage (MFS).
Investigating drug-polymer interactions using optical DSC
Researchers from the University of Hertfordshire’s School of Life and Medical Sciences collaborated with Linkam to provide an in-depth analysis into how the optical DSC450 and TASC can be used to characterise drug-polymer-excipient systems for pharmaceutical applications. Read the full case study here.
Webinar: From Ancient Relics to Life on Mars: Temperature-Controlled Experiments for Materials Characterisation
In advance of the Mars landing on 18 February 2021, members of the Analytical Chemistry group at Universidad del País Vasco / Euskal Herriko Unibertsitatea (University of the Basque Country) in Leioa, Spain presented their research on how temperature controlled experiments (including Raman spectroscopy, X-ray fluorescence and XRD analysis) can be used to characterise geological materials ranging from historical artefacts from the Roman empire to regolith samples from Mars.
The importance of being small: miniaturisation of freeze drying equipment
Developmental activities for freeze-dried products are dictated by the limited availability and high cost of newly developed active compounds, and by Quality-by-Design requirements. Laboratory-scale freeze dryers used for formulation and process development show an excessive variety of designs and instrumentation concepts, making scale-up activities a challenge. The development of miniaturised equipment may provide enormous benefits in terms of development times and costs.