Application Note

Unravelling the complexities of freeze-drying pharmaceuticals with advanced microscopy techniques

Linkam’s FDCS196 was used by researchers at the UK’s National Institute for Biological Standards and Control (NIBSC) and the University of Strathclyde to predict freeze-drying conditions for liposome-cryoprotectant mixtures (drug delivery systems), using light microscopy with a cryostage.

Studying Phase Transitions in Pharmaceuticals using Linkam’s DSC450 in conbination with TASC.

Polymorphism in pharmaceutical solids has great implications on both the processing and the performance of solid pharmaceutical products. This app note details work from the School of Pharmacy at UCL using TASC with our DSC450 to characterise polymorphic transitions in the pharmaceutical active compound flufenamic acid .